A full-scale 999 operation was launched as police, firefighters and ambulance crews raced to the scene on the A47 at Bushby, near Leicester, this morning.
The accident closed the busy Leicester-Peterborough route for several hours, triggering long traffic build-ups.
But it was set to be fully reopened later this afternoon.
The person taken to hospital hasn’t suffered “life-threatening or life-changing” injuries, said Leicestershire Police.
The collision on Uppingham Road in Bushby was reported to police just after 10am today.
As well as police and ambulances, fire crews from Leicester’s Eastern Station and Central Station also went to the accident scene.
“No persons trapped, two casualties.
“First aid being given and vehicles being made safe,” said Leicestershire Fire and Rescue Service earlier today.
“A47 closed in both directions.
“Both casualties being assessed by ambulance service, one casualty conveyed to hospital by ambulance.
“Incident handed over to the police.”